ASIZ/Research/Systems/Senolytics
Medicine · ι Far horizon

Senolytics

Senolytics are drugs that selectively clear 'senescent' cells — damaged cells that stop dividing but linger and secrete inflammatory signals that drive aging and disease.

Field
Medicine
Horizon
ι Iota · 2035–2042
Lead center
Living Systems
Maturity
Research frontier — early-stage, high-uncertainty
Why it matters

Removing these cells has reversed aspects of aging and disease in animals, making senolytics a leading approach to treating aging itself.

Where it stands

Several senolytic compounds are in human trials; proving safety and benefit in people is ongoing.

How ASIZ approaches it

The discovery loop, applied.

Through the Living Systems center, ASIZ aims the discovery loop at senolytics: frontier models survey the literature and simulate the possibilities, rank the experiments most likely to resolve the open questions, and partner labs run the decisive ones — with results shared openly.